High Accuracy Classification of Developmental Toxicants by In Vitro Tests of Human Neuroepithelial and Cardiomyoblast Differentiation

Cells

2022

Seidel Florian, Cherianidou Anna, Kappenberg Franziska, Marta Miriam, Dreser Nadine, Blum Jonathan, Waldmann Tanja, Blüthgen Nils, Meisig Johannes, Madjar Katrin, Henry Margit, Rotshteyn Tamara, Scholtz-Illigens Andreas, Marchan Rosemarie, Edlund Karolina, Leist Marcel, Rahnenführer Jörg, Sachinidis Agapios, Hengstler Jan G.

DOI: 10.3390/cells11213404

PMID: 36359802

Keyword: Alternative testing strategies · Developmental and reproductive toxicity · Drug screening · Gene expression · In vitro test · Induced pluripotent stem cells · Toxicogenomics · Transcriptomics