RISK-HUNT3R consortium
Scientific & Regulatory Advisory Board (SRAB)
Collaborations
RISK-HUNT3R consortium
RISK-HUNT3R consortium
RISK-HUNT3R gathers a total of 37 European partners from 11 countries forming a multidisciplinary panel of experts comprising academic and institutional reseachers, regulators from national and international authorities, as well as safety scientists from various industry sectors (SMEs and large industry).
Partners combine state-of-the-art expertise in human toxicology, molecular cell biology, tissue engineering, omics approaches, quantitative systems biology, human exposure, chemoinformatics, biokinetics, PBK modelling, biostatistics, and risk assessment. The scientific excellence is complemented by experts in management, dissemination, and training, making sure that the project runs smoothly and achieves maximum impact.
![RISK HUNT3R - Partner](https://www.risk-hunt3r.eu/wp-content/uploads/icon-partner-pin.png)
RISK-HUNT3R Partners
![RISK HUNT3R - Third Linked Partner](https://www.risk-hunt3r.eu/wp-content/uploads/icon-third-linked-partner-pin.png)
RISK-HUNT3R Linked Third Party
Title | Address | Description |
---|---|---|
UNIVERSITEIT LEIDEN (UL) | Rapenburg 70, 2311 EZ Leiden, Netherlands | |
RIJKSINSTITUUT VOOR VOLKSGEZONDHEID EN MILIEU | Antonie van Leeuwenhoeklaan 9, 3721 MA Bilthoven, Netherlands | |
FRAUNHOFER GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG EV | Nikolai-Fuchs-Straße 1, 30625 Hannover, Germany | |
CERTARA UK LIMITED | Level 2, Acero, 1 Concourse Way, Sheffield City Centre, Sheffield S1 2BJ, UK | |
UNIVERSITÄT KONSTANZ | Universitätsstraße 10, 78464 Konstanz, Germany | |
LIVERPOOL JOHN MOORES UNIVERSITY | Roscoe Court, 2 Rodney St, Liverpool L1 2UA, UK | |
EDELWEISS CONNECT GMBH | Hochbergerstrasse 60C, 4057 Basel, Switzerland | |
DANMARKS TEKNISKE UNIVERSITET | Anker Engelunds Vej 1 Bygning 101A, 2800 Kgs. Lyngby, Denmark | |
STEINBEIS GMBH & CO. KG FUER TECHNOLOGIETRANSFER | Willi-Bleicher-Straße 19, 70174 Stuttgart, Germany | |
ARTTIC | 37 Rue Bergère, 75009 Paris, France | |
BASF SE | Carl-Bosch-Straße 38, 67063 Ludwigshafen am Rhein, Germany | |
UPPSALA UNIVERSITET | von Kraemers allé 4, 751, 752 37 Uppsala, Sweden | |
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE | 101 Rue de Tolbiac, 75013 Paris, France | |
EUROPEAN MOLECULAR BIOLOGY LABORATORY / European Bioinformatics Institute | Wellcome Trust Genome Campus, Hinxton, Saffron Walden CB10 1SA, UK | |
BUNDESINSTITUT FUER RISIKOBEWERTUNG | Max-Dohrn-Straße 8-10, 10589 Berlin, Germany | |
RISE RESEARCH INSTITUTES OF SWEDEN AB | Forskargatan 20j, 151 36 Södertälje, Sweden | |
UNILEVER U.K. CENTRAL RESOURCES LIMITED | Colworth Laboratory, Colworth House, Sharnbrook, Bedford MK44 1LQ, UK | |
KAROLINSKA INSTITUTET | Nobels väg 5, 171 65 Solna, Sweden | |
KATHOLIEKE UNIVERSITEIT LEUVEN | Waaistraat 6, 3000 Leuven, Belgium | |
LATVIJAS ORGANISKAS SINTEZES INSTITUTS | Aizkraukles iela 21, Vidzemes priekšpilsēta, Rīga, LV-1006, Latvia | |
KOBENHAVNS UNIVERSITET | Nørregade 10, 1165 København, Denmark | |
LUNDS UNIVERSITET | Paradisgatan 5, 223 50 Lund, Sweden | |
UNIVERSIDAD POMPEU FABRA | Edif. Mercè, Plaça de la Mercè, 10-12, 08002 Barcelona, Spain | |
UNIVERSITAIR MEDISCH CENTRUM UTRECHT | Heidelberglaan 100, 3584 CX Utrecht, Netherlands | |
UNIVERSITAT WIEN | Universitätsring 1, 1010 Wien, Austria | |
STICHTING VU | Hoofdgebouw, De Boelelaan 1105, 1081 HV Amsterdam, Netherlands | |
BioDetection Systems B.V. | MATRIX Innovation Center, Science Park 406, 1098 XH Amsterdam, Netherlands | |
SIGNATOPE GMBH | Markwiesenstraße 55, 72770 Reutlingen, Germany | |
TISSUSE GMBH | Oudenarder Str. 16, 13347 Berlin, Germany | |
BIOCLAVIS LIMITED | 1345 Govan Rd, Glasgow G51 4TF, UK | |
NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETEN- SCHAPPELIJK ONDERZOEK | Anna van Buerenplein 1, 2595 DE Den Haag, Netherlands | |
COSMETICS EUROPE - THE PERSONAL CARE ASSOCIATION | Herrmann-Debrouxlaan 40, 1160 Oudergem, Belgium | |
L'OREAL SA | 14 Rue Royale, 75008 Paris, France | |
BAYER SAS | 355 Rue Fedor Dostoïevski, 06560 Valbonne, France | |
CHARLES RIVER LABORATORIES DEN BOSCH BV | Hambakenwetering 7, 5231 DD 's-Hertogenbosch, Netherlands | |
INDUSTRIA DE DISENO TEXTIL SA | 15143 Arteixo, A Coruña, Spain | |
MEDBIOINFORMATICS SOLUTIONS SL | Carrer dels Almogàvers, 165, 08018 Barcelona, Spain | |
BASF Metabolome Solutions GmbH | Tegeler Weg 33, 10589 Berlin, Germany |
![Prof. Dr. Bob VAN DE WATER](https://www.risk-hunt3r.eu/wp-content/uploads/universiteit-leiden.jpg)
Prof. Dr. Bob VAN DE WATER
Chair of the Division of Drug Discovery and Safety, Leiden Academic Centre for Drug Research (LACDR)
PROJECT COORDINATOR
![Dr. Mirjam LUIJTEN](https://www.risk-hunt3r.eu/wp-content/uploads/rijksinstituut-voor-volksgezondheid-en-milieu.png)
Dr. Mirjam LUIJTEN
Senior research toxicologist
![Dr. Annette BITSCH](https://www.risk-hunt3r.eu/wp-content/uploads/fraunhofer-gesellschaft-zur-forderung-der-angewandten-forschung-ev.jpg)
Dr. Annette BITSCH
Biologist/toxicologist, Head of the division Chemical Safety and Toxicology
![Dr Iain GARDNER](https://www.risk-hunt3r.eu/wp-content/uploads/certara-uk-limited.jpg)
Dr Iain GARDNER
VP, Head of Translational DMPK Science
![Prof. Dr. Marcel LEIST](https://www.risk-hunt3r.eu/wp-content/uploads/universitaet-konstanz.jpg)
Prof. Dr. Marcel LEIST
Head of the department of in vitro toxicology and biomedicine
![Prof. Dr. Mark CRONIN](https://www.risk-hunt3r.eu/wp-content/uploads/liverpool-john-moores-university.png)
Prof. Dr. Mark CRONIN
Professor of Predictive Toxicology
![Dr. Barry HARDY](https://www.risk-hunt3r.eu/wp-content/uploads/edelweiss-connect-gmbh.png)
Dr. Barry HARDY
Managing Director
![Eva Bay WEDEBY](https://www.risk-hunt3r.eu/wp-content/uploads/dtu.png)
Eva Bay WEDEBY
Senior Advisor at FOOD/DTU; Regulatory toxicologist
![Silvia Tangianu](https://www.risk-hunt3r.eu/wp-content/uploads/steinbeis-gmbh-and-co-kg-fuer-technologietransfer.jpg)
Silvia Tangianu
PhD Candidate
![Annette RINGWALD](https://www.risk-hunt3r.eu/wp-content/uploads/arttic.png)
Annette RINGWALD
Senior Consultant, Deputy Director
![Dr. Franziska ZICKGRAF](https://www.risk-hunt3r.eu/wp-content/uploads/basf-se.jpg)
Dr. Franziska ZICKGRAF
Experimental Toxicology and Ecology
![Prof. Dr. Per ARTURSSON](https://www.risk-hunt3r.eu/wp-content/uploads/uppsala-universitet.jpg)
Prof. Dr. Per ARTURSSON
Professor and head of the Drug Delivery Group
![Prof. Dr. Olivier TABOUREAU](https://www.risk-hunt3r.eu/wp-content/uploads/institut-national-de-la-sante-et-de-la-recherche-medicale.png)
Prof. Dr. Olivier TABOUREAU
Professor
![Dr. Ugis SARKANS](https://www.risk-hunt3r.eu/wp-content/uploads/european-molecular-biology-laboratory-european-bioinformatics-institute.jpg)
Dr. Ugis SARKANS
Team Leader - Functional Genomics Development
![Dr. Michael OELGESCHLÄGER](https://www.risk-hunt3r.eu/wp-content/uploads/bundesinstitut-fuer-risikobewertung.png)
Dr. Michael OELGESCHLÄGER
Head of Unit “Strategies for Toxicological Assessments”, Department Experimental Toxicology and ZEBET
![Prof. Dr. Ian COTGREAVE](https://www.risk-hunt3r.eu/wp-content/uploads/rise-research-institutes-of-sweden-ab.png)
Prof. Dr. Ian COTGREAVE
Senior Scientist and Strategist at RISE (Chemical and Pharmaceutical Safety); Professor of Toxicology (Karolinska Institute)
![Dr. Andrew WHITE](https://www.risk-hunt3r.eu/wp-content/uploads/unilever-uk-central-resources-limited.jpg)
Dr. Andrew WHITE
Science Leader in Computational Toxicology, Safety and Environment Assurance Centre (SEAC)
![Prof. Dr. Roland GRAFSTRÖM](https://www.risk-hunt3r.eu/wp-content/uploads/karolinska-institutet.png)
Prof. Dr. Roland GRAFSTRÖM
Professor, Institute of Environmental Medicine (IMM)
![Prof. Dr. Catherine VERFAILLIE](https://www.risk-hunt3r.eu/wp-content/uploads/katholieke-universiteit-leuven.jpg)
Prof. Dr. Catherine VERFAILLIE
Professor of Medicine, Director of the Stem Cell Institute Leuven
![Dr. pharm. Edgars LIEPIŅŠ](https://www.risk-hunt3r.eu/wp-content/uploads/latvijas-organiskas-sintezes-instituts.png)
Dr. pharm. Edgars LIEPIŅŠ
Leading Researcher
![Prof. Dr. Søren BRUNAK](https://www.risk-hunt3r.eu/wp-content/uploads/kobenhavns-universitet.jpg)
Prof. Dr. Søren BRUNAK
Research Program Director, Professor
![Dr. Ullrika SAHLIN](https://www.risk-hunt3r.eu/wp-content/uploads/lunds-universitet.png)
Dr. Ullrika SAHLIN
Associate Professor
![Dr. Manuel PASTOR](https://www.risk-hunt3r.eu/wp-content/uploads/universidad-pompeu-fabra.jpg)
Dr. Manuel PASTOR
Head of the Pharmaco Informatics Group of GRIB
![Prof. Dr. Roel VERMEULEN](https://www.risk-hunt3r.eu/wp-content/uploads/universitair-medisch-centrum-utrecht.jpg)
Prof. Dr. Roel VERMEULEN
Professor Environmental Epidemiology and Exposome Science
![Prof. Dr. Gerhard ECKER](https://www.risk-hunt3r.eu/wp-content/uploads/universitat-wien.jpg)
Prof. Dr. Gerhard ECKER
Head of Pharmacoinformatics Research Group, Dean of Faculty of Life Sciences
![Prof. Dr. Paul JENNINGS](https://www.risk-hunt3r.eu/wp-content/uploads/stichting-vu.png)
Prof. Dr. Paul JENNINGS
Head of Molecular and Computational Toxicology
![Dr. Bart VAN DER BURG](https://www.risk-hunt3r.eu/wp-content/uploads/biodetection-systems-b.v..jpg)
Dr. Bart VAN DER BURG
Director of Innovation
![Dr. Oliver PÖTZ](https://www.risk-hunt3r.eu/wp-content/uploads/signatope-gmbh.png)
Dr. Oliver PÖTZ
CEO/CSO
![Dr.-Ing. Eva DEHNE](https://www.risk-hunt3r.eu/wp-content/uploads/tissuse-gmbh.jpg)
Dr.-Ing. Eva DEHNE
Research Coordinator
![Joel McCOMB](https://www.risk-hunt3r.eu/wp-content/uploads/bioclavis-limited.png)
Joel McCOMB
Chief Executive Officer
![Dr. Dinant KROESE](https://www.risk-hunt3r.eu/wp-content/uploads/nederlandse-organisatie-voor-toegepast-natuurwetenschappelijk-onderzoek-tno.jpg)
Dr. Dinant KROESE
Senior Research Scientist
![Dr. Arianna GIUSTI](https://www.risk-hunt3r.eu/wp-content/uploads/cosmetics-europe-the-personal-care-association.jpg)
Dr. Arianna GIUSTI
Scientific Manager
![Dr. Gladys OUEDRAOGO](https://www.risk-hunt3r.eu/wp-content/uploads/l-oreal-sa.png)
Dr. Gladys OUEDRAOGO
Scientific Officer
![Dr. Remi BARS](https://www.risk-hunt3r.eu/wp-content/uploads/bayer-sas.png)
Dr. Remi BARS
Scientific Director Toxicology
![Dr. Walter WESTERINK](https://www.risk-hunt3r.eu/wp-content/uploads/charles-river-logo.jpg)
Dr. Walter WESTERINK
Section Head Flexible Innovation Team
![Héctor ALONSO](https://www.risk-hunt3r.eu/wp-content/uploads/industria-de-diseno-textil-sa.jpg)
Héctor ALONSO
Sustainability-Science, Technology and Innovation Manager
![Dr. Laura FURLONG](https://www.risk-hunt3r.eu/wp-content/uploads/medbioinformatics-solutions-sl.png)
Dr. Laura FURLONG
CO-founder and Chief Scientific Officer
Linked Third Party
![Prof. Dr. Hennicke KAMP](https://www.risk-hunt3r.eu/wp-content/uploads/basf-se.jpg)
Prof. Dr. Hennicke KAMP
Managing Director, Toxicologist (ERT)
BASF Metabolome Solutions GmbH
Scientific & Regulatory Advisory Board (SRAB)
Scientific & Regulatory Advisory Board (SRAB)
The RISK-HUNT3R project works in close collaboration with an independent international Scientific & Regulatory Advisory Board (SRAB) composed of a representative panel of independent experts from regulatory agencies and industry. The SRAB provides advice on relevant issues from a scientific, regulatory, industrial and ethical perspective. As such, their expertise and feedback will be of great value to ensure relevance of the various project case studies, but also on a higher level regarding. for example, scrutiny of overall work and results quality, and warranting scientific and technological state of the art.
The members of the SRAB are the following:
- Thomas STEGER-HARTMANN, Bayer AG, Research & Development, Pharmaceuticals
- Matthias HERZLER, The German Federal Institute for Risk Assessment (BfR)
- Nicholas BALL, The Dow Chemical Company
- George KASS, European Food and Safety Authority (EFSA)
- Magdalini SACHANA, Organisation for Economic Co-operation and Development (OECD)
- Stephen FERGUSON, National Institutes of Health/National Institute of Environmental Health Sciences (NIH/NIEHS)
- John WAMBAUGH, U.S. Environmental Protection Agency (US EPA)
Collaborations
Collaborations
RISK-HUNT3R & JRC
RISKHUNT3R actively collaborates with the Joint Research Centre at the level of validation of test methods and the implementation of high-throughput testing, assessment of TTC methods, and definition of strategies toward completely animal-free safety testing. Moreover, JRC will actively participate in the communication to international stakeholders, including regulatory agencies, national reference laboratories, European 3R centres, and industry stakeholders.
RISK-HUNT3R & Tox21 (US EPA, NIH, NIEHS/NTP, FDA)
The Tox21 program is a collaboration among four US government agencies to develop new ways to rapidly test whether substances can have an adverse effect on human health. The approaches taken in Tox21 are complementary to efforts in RISK-HUNT3R in that they also employ NAMs such as high-throughput transcriptomics and other in vitro and in silico-based tests. The application of NAMs in NGRA is a common goal. Several representatives of the Tox21 program are members of the RISK-HUNT3R Scientific and Regulatory Advisory Board (SRAB). To ensure mutually beneficent knowledge exchange between Tox21 and RISK-HUNT3R, regular web-based or physical meetings are organised and working groups are established. These working groups are dedicated to particular topics of interest to both projects and serve to quickly disseminate knowledge and approaches.
Collaboration focus areas:
- High-throughput methods for NGRA
- AOP network-based system toxicology
- High-throughput PBK models
- Threshold of toxicological concern (TTC) approaches
- Integration of advanced multi-physiological systems (MPS, including organ-on-a-chip models) for risk assessment
ASPIS
RISK-HUNT3R is one of three projects in the research cluster ASPIS: “Animal-free Safety assessment of chemicals: Project cluster for Implementation of novel Strategies”. Together with the projects ONTOX and PrecisionTOX, these represent Europe’s €60M effort towards the sustainable, animal-free and reliable chemical risk assessment of tomorrow.