SimRFlow: An R-based workflow for automated high-throughput PBPK simulation with the Simcyp® simulator

Frontiers in Pharmacology

2022

Khalidi Hiba, Onasanwo Anthonia, Islam Barira, Jo Heeseung, Fisher Ciarán, Aidley Rich, Gardner Iain, Bois Frederic Y.

DOI: 10.3389/fphar.2022.929200

PMID: 36091744

Keyword: PBPK modelling · R · Automated data collection · High-throughput · Modular workflow · Pharmacokinetics · Simcyp simulator · Simulation