SimRFlow: An R-based workflow for automated high-throughput PBPK simulation with the Simcyp® simulator

Frontiers in Pharmacology
2022
Khalidi Hiba, Onasanwo Anthonia, Islam Barira, Jo Heeseung, Fisher Ciarán, Aidley Rich, Gardner Iain, Bois Frederic Y.
DOI: 10.3389/fphar.2022.929200
PMID: 36091744
Keyword: PBPK modelling · R · Automated data collection · High-throughput · Modular workflow · Pharmacokinetics · Simcyp simulator · Simulation