The integrated stress response-related expression of CHOP due to mitochondrial toxicity is a warning sign for DILI liability

Liver International
2024
Vlasveld Matthijs, Callegaro Giulia, Fisher Ciarán, Eakins Julie, Walker Paul, Lok Samantha, van Oost Siddh, de Jong Brechtje, Pellegrino-Coppola Damiano, Burger Gerhard, Wink Steven, van de Water Bob
DOI: 10.1111/liv.15822
PMID: 38217387
Keyword: CHOP · drug-induced liver injury · high-throughput screening · integrated stress response · mitochondrial toxicity