Transcriptomic-based evaluation of trichloroethylene glutathione and cysteine conjugates demonstrate phenotype-dependent stress responses in a panel of human in vitro models

Archives of Toxicology
2023
Capinha Liliana, Zhang Yaran, Holzer Anna-Katharina, Ückert Anna-Katharina, Zana Melinda, Carta Giada, Murphy Cormac, Baldovini Jenna, Mazidi Zahra, Grillari Johannes, Dinnyés András, van de Water Bob, Leist Marcel, Commandeur Jan N. M., Jennings Paul
DOI: 10.1007/s00204-022-03436-6
PMID: 36576512
Keyword: cytotoxicity · glutathione conjugation pathway · hazard identification · multi-organ toxicity · transcriptomics